Sucrose intolerance

From Wikipedia, the free encyclopedia
Sucrose intolerance
Classification and external resources

Sucrose
ICD-10 E74.3
ICD-9 271.3
OMIM 222900
DiseasesDB 29844

This article may be too technical for most readers to understand. Please help improve this article to make it understandable to non-experts, without removing the technical details. The talk page may contain suggestions. (November 2012)
Sucrose intolerance, also called congenital sucrase-isomaltase deficiency (CSID)[1] or Sucrase-isomaltase deficiency,[2] is the condition in which sucrase, an enzyme needed for proper metabolism of sucrose (sugar), is not produced in the small intestine.
It is more common among the Inupiat.[3]
Contents [hide]
1 Overview
2 Symptoms of Sucrose Intolerance
3 See also
4 References
5 External links
Overview [edit]

Sucrose (also known as saccharose) is a disaccharide and is a two-sugar chain composed of glucose and fructose which are bonded together. A more familiar name is table, beet, or cane sugar. In most cases, sucrose intolerance is an autosomal recessive genetic metabolic disease, and involves deficiency in the enzyme sucrase, which breaks apart the glucose and fructose molecules. Monosaccharides, or single sugar units, are absorbed directly into the blood. However disaccharides are consumed, they must be broken down into monosaccharides by enzymes in the intestines before they can be absorbed. Sucrose can sometimes be found in the stool as an indication of an inability to digest and absorb sucrose in the body.
A deficiency of sucrase may result in malabsorption of sugar, which can lead to potentially serious symptoms. It is important for those with sucrose intolerance to minimize sucrose consumption as much as possible. Foods such as fruit and starch can help heal the body and reduce some symptoms.[citation needed] Supplements can be taken as a substitution of the enzyme missing or to introduce healthy bacteria into the immune system.
Sucrose Intolerance (Congenital sucrase-isomaltase enzyme deficiency) can be caused by genetic mutations (the common ones being SI and SII), in which both parents must contain this gene in order for the child to carry the disease. Sucrose intolerance can also be caused by irritable bowel syndrome, aging, or small intestine disease. There are specific tests used to determine sucrose intolerance. The most common tests are the sucrose breath test, genetic analysis or enzyme activity determination, which takes place in the small intestine.
Symptoms of Sucrose Intolerance [edit]

Abdominal cramps and bloating
Diarrhea and constipation
Vomiting
Hypoglycemia and headaches
Poor weight gain and growth
Upper respiratory tract and viral infections
Anxiety and heart palpitations
Excess gas production
See also [edit]

Fructose malabsorption
Gastroenterology
Lactose intolerance
Sucrase-isomaltase

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: